Creatine
(586)
Creatine, identified by its PubChem CID 586, is an amino acid derivative with the molecular formula C4H9N3O2.
Creatine is one of the most extensively researched supplements in the health industry. Organically found in fish and red meat, creatine is critical to the ATP cycle in our bodies.
Benefits of Creatine
Thorough research has show that creatine supplementation can increase muscular, cardiovascular, and cerebral function. However, many new studies are suggesting advantages beyond the three named.
MUSCLE STRENGTH
Creatine supports muscle strength by helping your body produce quick energy during high-intensity effort. By increasing phosphocreatine stores in muscle, creatine helps fuel short, powerful movements like lifting, sprinting, and repeated bursts of work.
When paired with consistent resistance training, creatine has been shown to support gains in strength and lean muscle mass over time.
Source 01, Source 02
MUSCLE RECOVERY
Creatine may help support post-workout recovery by replenishing energy stores and helping the body respond to the stress of intense training. Research suggests creatine can support recovery between bouts of exercise and may help reduce markers associated with muscle damage.
Source 01, Source 03
COGNITIVE FUNCTION
Because creatine helps support cellular energy metabolism, researchers have studied its role in cognitive performance. Current evidence suggests creatine supplementation may support areas like memory, attention, and processing speed — especially when the brain is under higher demand.
Source 04, Source 05
CELLULAR ENERGY
At the center of creatine’s benefits is energy.
Creatine helps form phosphocreatine, a fast-acting energy reserve your cells use to regenerate ATP — the body’s primary energy currency. This system helps support tissues with high energy needs, including muscle and brain.
Source 01, Source 06
Potency
"Potent" - chemically or medicinally effective.
While creatine is extremely stable in a powder form, it can rapidly break down in liquid solutions.
Creatine monohydrate is one of the most researched supplements in sports nutrition. In dry powder form, it’s highly stable. But when diluted into a liquid, it breaks down into creatinine; an inactive byproduct your body gets rid of. The more creatine breaks down, the less active creatine is available for your body to use.
Potency isn’t about how much creatine is listed on the label. It’s about how much creatine is still intact when it reaches you.
Creatine stability is easily affected by water, time, pH, and temperature. These variables are always changing during manufacturing, shipping, storage, and months on a shelf; making shelf stable creatine drinks difficult to create.
Source 01, Source 08
Some products use newer forms of creatine, including buffered, encapsulated, or liposomal creatine, to help improve stability. These technologies can help slow degradation, but slowing degradation is not the same as stopping it. Leading encapsulated creatine technologies show that creatine still breaks down in beverage applications.
Source 08, Source 09
DRINK 586 keeps the creatine, electrolytes, and flavoring dry inside the cap until the moment you’re ready to drink. Anytime, Anywhere.
Creatine and Kidneys
Despite raising markers used when testing kidney health, creatine supplementation does not appear to damage kindey function.
Creatinine is commonly measured in bloodwork as a kidney-function marker. Because creatine can naturally convert into creatinine, creatine supplementation can sometimes increase creatinine levels.
That does not automatically mean kidney damage is occurring. Current research has found that creatine supplementation does not appear to impair kidney function in healthy people when used at recommended doses.
Source 01, Source 10
Formula
DRINK 586 takes pride in providing consumers with daily products, which is why we promise to deliver transparency, reason, and purpose regarding each of our products and their ingredients.
5g CREATINE MONOHYDRATE
5g of micronized creatine monohydrate from Creapure®. The clinically recommended dosage paired with premium creatine to provide only the best for your daily creatine needs.
360mg ELECTROLYTE BLEND
220mg of sodium, 120mg of potassium, and 20mg of magnesium formulated to replenish electrolytes and enhance taste.
SWEETENERS
3 sweetener blend consisting of stevia, monk fruit, and cane sugar to naturally sweeten the drink and aid in creatine absorption.
FLAVORING
Natural flavor powders extracted from the fruit itself to provide a refreshing, juice like experience.
COLORING
Natural, plant based color powders to improve the DRINK586 experience.
Sources and Peer Reviewed Journals
S01 / CREATINE OVERVIEW
Kreider, Richard B., et al. “International Society of Sports Nutrition Position Stand: Safety and Efficacy of Creatine Supplementation in Exercise, Sport, and Medicine.” 2017. Journal of the International Society of Sports Nutrition
S02 / MUSCLE STRENGTH
Desai, Ishaan, et al. “The Effect of Creatine Supplementation on Resistance Training-Based Changes to Body Composition: A Systematic Review and Meta-Analysis.” 2024. Journal of the International Society of Sports Nutrition.
S03 / RECOVERY
Wax, Benjamin, et al. “Creatine for Exercise and Sports Performance, with Recovery Considerations for Healthy Populations.” 2021. Nutrients.
S04 / COGNITIVE FUNCTION I
Xu, Chen, et al. “The Effects of Creatine Supplementation on Cognitive Function in Adults: A Systematic Review and Meta-Analysis.” 2024. Frontiers in Nutrition.
S05 / COGNITIVE FUNCTION II
Avgerinos, Konstantinos I., et al. “Effects of Creatine Supplementation on Cognitive Function of Healthy Individuals: A Systematic Review of Randomized Controlled Trials.” 2018. Experimental Gerontology.
S06 / CELLULAR ENERGY
Clark, Joseph F. “Creatine and Phosphocreatine: A Review of Their Use in Exercise and Sport.” 1997. Journal of Athletic Training.
S07 / CREATINE & STABILITY
Ganguly, Subhasis, Shivanand Jayappa, and Alekha K. Dash. “Evaluation of the Stability of Creatine in Solution Prepared from Effervescent Creatine Formulations.” 2003. AAPS PharmSciTech
S08 / ALTERNATIVE STABILITY
Glanbia Nutritionals. “CreaBev®: Soluble and Stable Creatine Monohydrate for Superior Performance Beverages.” 2024. Glanbia Nutritionals.
S09 / BUFFERED CREATINE
Jagim, Andrew R., et al. “A Buffered Form of Creatine Does Not Promote Greater Changes in Muscle Creatine Content, Body Composition, or Training Adaptations than Creatine Monohydrate.” 2012. Journal of the International Society of Sports Nutrition.
S10 / CREATINE & KIDNEYS
Longobardi, Ilaria, et al. “Is It Time for a Requiem for Creatine Supplementation-Induced Kidney Failure? A Narrative Review.” 2023. Nutrients.
S07 / CREATINE & STABILITY
Ganguly, Subhasis, Shivanand Jayappa, and Alekha K. Dash. “Evaluation of the Stability of Creatine in Solution Prepared from Effervescent Creatine Formulations.” 2003. AAPS PharmSciTech
S08 / ALTERNATIVE STABILITY
Glanbia Nutritionals. “CreaBev®: Soluble and Stable Creatine Monohydrate for Superior Performance Beverages.” 2024. Glanbia Nutritionals.